Saturday, August 31, 2019

Marty King Essay

Erik Erikson had numerous contributions to the field of psychology; many of which involved his developmental theory. Erikson has been compared to Sigmund Freud; as both men believed that humans develop in stages. Erikson however, believed Freud to be misguided, as Erikson believed that developmental process is one which occurs throughout one’s lifespan; whereas Freud believed that a human’s personality developed by the age of five (Chen, 2007). Erikson published numerous books on human development; as well as issues including the generation gap, changing sexual roles and racial tensions. This quantitative research paper however, discusses Erikson’s eight stages of development and how each stage correlates with symptoms of borderline personality disorder. Each of Erikson’s eight developmental stages consists of certain elements (crises), which if not resolved will result in negative outcomes. The researcher believes that when crises are not resolved within Erikson’s developmental stages, it predisposes individuals to borderline personality disorder. In order to prove this hypothesis, the researcher will conduct quantitative research on the causes and symptoms of borderline personality disorder and the negative outcomes of Erikson’s eight developmental stages; the phenomenological research will then be compared. Borderline personality disorder has been widely studied over the past several decades; however, there is limited research on what childhood (birth to age eighteen) attributes contribute to the onset of BPD. Approximately two percent (up to ten million) of adults in the U. S. are diagnosed with BPD; accounting for twenty percent of psychiatric hospitalizations (NIMH, 2008); many cases of BPD go undiagnosed. Genetic factors have been primarily studied in the past as the biological cause of BPD; however recent research shows that forty to seventy-one percent of BPD patients were sexually abused as children (NIMH, 2008), approximately seventy-three percent report physical abuse and emotional abuse and neglect are also commonly reported in BPD cases. These statistics indicate that there is reason to believe that childhood trauma could significantly predispose a person to BPD. While research as to the possible causes of BPD has been conducted, the researcher proposes that a quantitative study be conducted in order to collect phenomenological data from various studies, for comparison to Erikson’s eight stages of development. The reason for this strategy is that by comparing the results of numerous studies, the researcher can produce â€Å"the bigger picture†, of what predisposes individuals to BPD; thus increasing the probability of successful recovery. The researcher chose Erikson’s eight developmental stages as model for comparison because the eight crises depicted in this model demonstrate the traumas indicated in many BPD cases. When the eight crises are not resolved, the results correlate with BPD symptoms. The researcher aims to prove that individuals who do not resolve the eight negative crises of Erikson’s developmental model; thus suffering some form of childhood trauma, are predisposed to BPD as adults. As mentioned previously, the information proving this hypothesis can be used to improve treatment options for BDP patients. The researcher for this study would like to see a reduction in hospitalization as a treatment for BPD patients; and instead implement alternative methods, such as assisting patients through Erikson’s eight stages. Assisting patients through the eight stages will allow them to re-learn emotional skills and abilities; such as coping skills. The researcher’s professional background in BPD clinical work has allowed significant insight into the difficulties of BPD treatment. Due to the immense amount of physical and emotional energy needed to work with BPD patients; many professionals tend to provide affirmation of the history of failure and poor coping skills by treating the patient with sympathy instead of empathy. The researcher believes that understanding the reasoning behind BPD patient behavior will improve the patient’s ability to improve poor coping skills. This change in professional behavior will reduce the feelings of being burnt out and tired because the professional will be able to support the success of the patient instead of doing the work for them. Currently, there is an attitudinal barrier between the professional and the patient which results in a failure to understand the condition of BPD. The researcher hopes to promote an understanding of BPD patient behavior; behaviors which many clinical professionals find exasperating. In increasing understanding of the development of BPD behaviors, clinicians will be better equipped to work with patients in an inclusive partnership rather than feeling they are exceeding appropriate boundaries. Literature Review Erikson’s Eights Stages of Development The â€Å"Eight Stages of Development†, the process of socialization, were developed by Erik Erikson in 1956 (Child Institute Center, n. d. ). Erikson had extensive experience in psychotherapy; including children and teens of all social classes. Erikson believed that each stage presented a â€Å"psychosocial crisis† in which an individual must experience, learn and resolve in order to successfully manage the next step. Erikson’s eight stages are represented in Figure 1. The eight stages are based on the â€Å"interaction of three different systems: the Somatic system, the ego system, and the societal system† (Keenan, p. 22, 2002). The somatic system refers to the biological processes of human functioning. The ego system are the central thinking and reasoning processes (2002); and the societal system is the process an individual goes through as he becomes integrated into his society. Erikson believed that the eight stages occurred in order and each stage represented a crisis which had to be resolved by the individual. Whether the crisis was completed successfully or not would be the deciding factor on how successful the next stage would be. If the crisis was not mastered, then the individual would be ill prepared to deal with the next stage of development; this trend would continue throughout all the stages. Erikson did believe that the eight stages were relevant throughout life and that he linked a crisis to each stage because that is when the crisis was most salient (Cohen, 2007). Oral-Sensory Stage. In this first stage (trust/mistrust), the first year of life is defined as the time for building trust; this is accomplished by the infant learning trust through the parent or caregiver’s actions and responses to the infant’s needs. Feeding is the focal point of Erikson’s first stage; when the child cries for food, the parent will feed and comfort the infant. If the child is neglected, he will learn to be mistrustful. Erikson also believed if trust was not established in the first stage, the child could become â€Å"frustrated, withdrawn, suspicious, and will lack self-confidence† (Sharkey, 1997). Muscular-Anal Stage. The second stage (autonomy/doubt) consists of ages one through two years old. During this stage the child is face with the development of self-control which is accomplished by a supportive atmosphere. If basic trust was not developed in stage one, the child will have difficulty in establishing self control in stage two, resulting in a lack of self-esteem (Sharkey, 1997). If the parent is too controlling, or does not provide enough structure the child can become doubtful of himself and the environment around him.

Friday, August 30, 2019

Common man Essay

At one level, the thesis is then just another callow compromise by the author in a life that he would call hollow, servile, and insincere. He is a weak and miserable man. Early in life, he was instilled with the desire to live according to what Bolles (1985) referred to as the three boxes of life, a desire that most middle-class parents bequeath to their children in the developing world. The three boxes of life being: foreign Western education, or rather training; high paying professional work in the West or the Middle East; and lastly a cushy retirement plan in North America and/or Europe, or a dollar-indexed pension to be paid in the home country. In other words, to borrow the incisive language of Malcolm X, my social milieu spoke to me in the following way: try to change your status from that of a field slave in the developing world to a house slave in a developed country so that you are of more use to the master and get to live a relatively comfortable life. On no account are you to forge a common cause with your fellow field slaves and work towards a new reorganization of the plantation so that all can live with dignity. You are, of course, allowed to be compassionate towards the lower orders, give charity, and urge them to be like you in the lust to emulate the master. Thus, I came to view myself as a rat, in all senses of the word, and my country as a sinking ship. Foreign education was the life boat on which I could get out of the ship and serve with a smile those very institutions and interests that had boarded and scuttled not only my ship but many others like it. As for those drowning in the decks below, the thought never really entered my mind. I now freely admit that I could not escape the clutches of the first box even when I became aware that I would be serving the very interests that were antithetical to what I thought represented the best in humanity. My ensnarement was due not so much to the strength of the box but to some path dependency processes which were accentuated largely by my own weaknesses, an unhealthy craving for wealth and status, and, lastly, craven cowardice that has made me so far, to quote Hamlet, ‘bear the ills we have than fly to those that we know not of.’ The jury is still out on the second and third boxes though. I hope the thesis will help me make my escape from them.

Thursday, August 29, 2019

Confucius Essay Example | Topics and Well Written Essays - 500 words

Confucius - Essay Example Born in Qufu, an important city of Lu state of China, by 551 B.C. in a respectable family with military background, Confucius led a very humble, modest and pious life. (Yao, 2000) He always laid stress upon virtue, chastity, humility, benevolence and generosity, the admirable rules aptly attributed to the teachings of the Abrahamic faiths too. Confucianism vehemently maintains unflinching belief in the afterlife and the concepts of reward and punishment entirely based upon man’s activities and behavior during his life on the earth. It is therefore the religion strongly preaches the observing of the good social and moral behavior while interacting with the other members of society. Golden rule enjoys the status of pivotal point of Confucianism, as all the concepts and teachings of the faith revolve around the same. The rule emphasizes upon treating the other members of society in the same manner as one wishes to be treated by others. Moreover, one should not inflict the pain and agony to others, which he does not like for himself or cannot forbear and endure the same. The same is also applied in the exchange of presents, where an inferior or sub-standard article should not be given to the other by preserving a superior one for oneself. Similarly, Confucianism prohibits man from inflicting any type of unpleasantness upon others by applying ill intentions, as the universal laws of retaliation may reciprocate the same to the wrong-doer. Consequently, the rule lays stress upon observing of virtue, kindness, honesty and integrity towards the fellow beings, and strictly forbids adopting of the social evils like wickedness, fraud, cheating, lying, fornication, adulte ry and deceit etc at any cost, as such immoral and cruel actions not only invite difficulties and adversity in human life, but also man will have to be responsible for such misdeeds in the life Hereinafter. Confucianism concentrates upon the best and intimate relationships between the family

Wednesday, August 28, 2019

Comparison of state funding strategies Essay Example | Topics and Well Written Essays - 500 words

Comparison of state funding strategies - Essay Example Rather, three major modalities are implemented. These are work-study, loans, and grant. The benefit is that it expands the number of beneficiaries as it addresses different areas of educational funding needs. On a yearly basis, an amount of $5.35 billion is said to be spent in this regard. The new scheme comes to replace what was known as Robin Hood, and emerges with the benefit of allowing for better equitability, less divisiveness and better funding, all of which can be said to be the strength of the new scheme. Figure 1 below shows how different students and institutions have made use of the funding scheme. Unlike Texas where the funding scheme is directly focused on the student spending to the tune of $5.35 billion, the scheme in New York looks more into the generation and issuance of grants to educational institutions. What this means is that even though this money is non-repayable, it must be contested for by interested educational institutions through grant writing (NYSED, 2014). Here, the strength that can be seen of the state funding scheme used in New York is that it allows for competitiveness among institutions, where more deserving institutions that can justify their course through the grant writing receive more. Comparing this to what prevails in Texas, however, a major loophole can be found when it comes to equitable distribution of the national cake. This is because through no fault of their own, there will be students who will be denied necessary state funding since their institutions cannot convince state authorities as to why their institutions should receive grants. It must be noted that students have both direct and indirect benefits from state funds, including the savings made by parents on the payment of fees. Alabama, on the other hand, has a very unique state funding scheme that is meant purposely for college students (Alabama Commission on Higher Education, 2013). Unlike the first two strategies discussed, this

Tuesday, August 27, 2019

Arguement essay ---education related( preferred differences between

Arguement ---education related( preferred differences between chinese and western education - Essay Example Education happens through exploration, preparing or teaching under the direction of instructors and can too be self-teaching. Teachers have the obligation to instruct their learners in the most ideal ways that could be available. Educating is the giving of information, aptitudes and qualities to the learners through the use of suitable teaching methods that are satisfactory. Through the routines the general public has the capacity accomplish set objectives and instructive destinations (Chua 67). Good teachers know how to viably teach their students the skills they really require in life based on the numerous teaching techniques. Therefore, educators must be adaptable in their teaching methods and frequently modify their styles to have the capacity to suit all students, thus effective education. However, the obvious question that has led to heated debates is â€Å"what makes the difference in education?† The difference comes as a result of different education systems that are adopted by the various nations; most countries use different approaches in their teaching and learning. This brings the big difference that is between Chinese system of education and that of the Westerners. First and foremost, the most detectable contrast at the center school and secondary school level is the size of the classes (Hsu, and Yuh-Yin 17). In china teachers regularly teach two classes with 55 to 60 students. While on the other hand, American secondary teachers regularly teach five or six classes with class sizes extending from 25 to 30. It should be noted that students have got different behavioral entries based on their psychological development, socio-economic background and culture as well. This makes it very important that the teacher-student ratio be manageable, so that every st udent gets special attention. In Western culture, students are free to ask and answer questions in order to get clarifications, they

Monday, August 26, 2019

Prototyping in Graphic design Research Paper Example | Topics and Well Written Essays - 750 words

Prototyping in Graphic design - Research Paper Example Graphic designers do not generate attributes and abstract relationships then derive the suitable object to consider. They instead always generate a design model and then find out its specifications. This paper looks at how design tools enable graphic designers to create functional prototypes of ever-present user interfaces. This scholarly compilation of modern essays applies quantifiable study to the graphic design practice. The whole book heartens designers to develop practices that are research-oriented which are more all-encompassing of audience input along with interdisciplinary proficiency. This is an educational book for any teacher of design. Buxton advises us to spotlight more on the blueprint of the design development than the product design. An efficient method to do this, he cites, is by â€Å"sketching† (demos, prototypes, sketches, simulations, models). Throughout this book he as well heartens teachers to incorporate into their classrooms additional scholarship, a history sense and a joint approach to the process of design. The book has provoking interviews along with genuine world examples. This is a useful guide to managing and forming a graphic design business. It is increasingly helpful for learners as many are trying to start on their careers at first as freelancers as a substitute of employees. This book outlines a greatly helpful timeframe of graphic design from 1890 to 2000. In essence, it is an efficient sketch of the history of graphic design, allowing learners to speedily put designers along with their work into chronological background. This collection of current essays and case studies initiates designers to research tools made particularly for graphic design. It covers â€Å"research through design, research into design and research for design.† Most of the research methodologies regard design as a segment of an integrated system. (11) Martin, Bella, and Bruce M. Hanington. Universal

Sunday, August 25, 2019

Microeconomics Essay Example | Topics and Well Written Essays - 250 words - 2

Microeconomics - Essay Example However, the situation is beneficial to the country in the long term. Currently, US citizens have to cope with high interest rates and high mortgage rates due to the country’s account deficit. The current situation may indicate that the country’s rate of investment is exceeding its GDP. Investment is not a bad thing for the country although it might cause short-term financial strains on the citizens and unfavorable trade balance (Barschel, 2007). However, long-term benefits may propel US to high levels of economic performance. None of the current economic solutions can be applied to reverse the situation. In order to contain the situation, the government needs to encourage savings and reduce borrowings among its people. This will involve giving people the right education in order to sensitize them on the importance of saving within the country. Increasing tax rates will also reduce borrowing and increase savings. The government also needs to cut the countries imports while it promotes exports. Oil accounts for $140 billion of the total US imports. The government should promote energy conservation and use of alternative energy in order to cuts oil imports and to promote favorable trade

Saturday, August 24, 2019

Give your reaction to the story, your impression of the story, how it Essay - 1

Give your reaction to the story, your impression of the story, how it relates to your life, compare it to another story, or anything--as long as it involves an assigned story you read - Essay Example â€Å"The Rime† and â€Å"Ode† use vibrant imagery, where for â€Å"The Rime,† it contributes to the effectiveness of the plot in depicting scintillating events and characters, while for â€Å"Ode,† it underscores the â€Å"natural† essence of insight. When Coleridge says: â€Å"As idle as a painted ship/Upon a painted ocean,† this image is quite fitting to the situation of the sailors, not just as an effective â€Å"picture† of what is occurring, but as a representation of their hopelessness. â€Å"Ode† employs numerous elemental imagery, such as sun, moon, mountains, and flowers. They are natural and seem simple at first, but they are also viewed as â€Å"grand† examples of nature that implicate the religious theme of â€Å"remembering† the natural nature of â€Å"remembering† and they are connected to the raw and natural dispositions of children, whom Wordsworth attests as the bosom of meaning and a sourc e of true insight. Irony is one of the most interesting figures of speech in literature and Coleridge and Wordsworths apt use of it has made their works more intellectually stimulating. These lines demonstrate the irony of being surrounded by water and yet suffering from thirst in â€Å"The Rime†: â€Å"Water, water, every where,/ Nor any drop to drink† (Coleridge). It is similar to being surrounded by food, but not being able to eat them because they are poisoned. Situational irony is also present in how the mariner lives on, when he is the main reason that his co-crew members died. Nevertheless, â€Å"The Rime† shows that life is not better than death if it is cursed to be filled with guilt. â€Å"Ode† applies irony when it says that celestial knowledge is only held during childhood, instead of being learned throughout adulthood. â€Å"Heavens† (Wordsworth 67) knowledge submerges into a process of â€Å"forgetting† (Wordsworth 59) and it is only through â₠¬Å"remembering† (Wordsworth 59) that people can regain true insight about life. These poem share religious

Friday, August 23, 2019

Risk Management Strategy Coursework Example | Topics and Well Written Essays - 750 words

Risk Management Strategy - Coursework Example However, this is not usually the case since sometimes risks emerge that creates an impact on the delivery, costs, schedules and performance of the project (Greenhalgh et al., 2010: p. 4). This therefore requires the project team to device an effective risk management plan to deal with the emerging uncertainties. A risk is any uncertain event whose occurrence affects the performance of a project. A risk management strategy describes the specific management techniques and standards to be applied and the responsibilities for achieving an effective risk management procedure. The objectives of this risk management strategy is to protect the organisation, employees, clients and any other volunteers who are involved in the implementation of the NHS Summary Care Record (SCR) project (Goundrey-Smith, 2012:p.67). The scope of this risk management plan includes the process of identifying, analyzing and managing risks. This risk management plan provides guidelines on performing, recording, monitoring and reporting risk management activities throughout the project life cycle (Greenhalgh et al., 2010: P.7). Risks related to the use of SCR systems must be identified and documented appropriately using the PRINCE2 project management method. The various risks and threats that may emerge as a result of using electronic systems to store and manage patients information must be identified and mitigated appropriately(Greenhalgh et al., 2008: p.3) A good risk management strategy for SCR stipulates the procedures for identifying the risks, assessing the impact of the risks, planning for the risks, implementing the strategy and communicating the strategy to the people concerned(Goundrey-Smith, 2012:p.32). The project co-ordinator/ manager will work in collaboration with the project team to identify, analyze and manage risk during the project life cycle. The following sections outline the various steps to the project

Political Contributions by Corporations Essay Example | Topics and Well Written Essays - 2000 words

Political Contributions by Corporations - Essay Example Second, the evidence suggests that in many cases the desired political favors have been and are granted. More specifically, the data demonstrates a correlation between political contributions and benefits allocated among corporations. Finally, with respect to the effect of this link between political contributions and favors granted, the literature suggests some positive characteristics as well as some negative characteristics. Some corporations, for instance, have been granted special access to international markets that generates profits and some employment benefits for Americans whereas some corporations have abused the benefits conferred upon them to the detriment of Americans more generally. This paper will examine the case of Enron because this case is illustrative of the many issues surrounding political contributions by corporations; to be sure, the Enron case is one of extremes, not experienced in all cases, but these extremes demonstrate the dangers inherent in unregulated or poorly regulated systems for dealing with political contributions by corporations. ... From a conceptual framework, scholars have approached connections between corporations and politicians in a variety of ways. Some, for example, have examined how connections to politicians affect a corporation's underlying valuation or stock prices (Faccio and Parsley, 2006). The research has found a correlation between certain connections, whether in the form of lobbying or direct political contributions, and this data is well-known by corporations and corporate decisions makers. Because the value of stock prices can be sustained or increased, to some degree, by pursuing political connections, corporate executives are keen to align themselves with some or many politicians. In addition, scholars have also approached the connections between corporations and politicians by noting which corporations have been bailed out with government funds during periods of economic distress, and the extant of the political contributions made by these bailed-out corporations; interestingly enough, the data demonstrates that corporations with stronger political connections, whether in the form of lobbying or political contributions, are more likely to receive governmental bailouts than corporations with less substantial political connections (Faccio, Masulis, and McConnell, 2006). Two other areas of inquiry, of particular relevance in the Enron case, are how connections between political contributions by corporations to politicians affect its export business and its corporate sales through government contracts (Agrawal and Knoeber, 2001) as well as the ability of such corporations to secure certain tax benefits at the state or federal level (Gupta and Swenson, 2003). A review of the literature, therefore demonstrates that there are many important reasons for corporations to

Thursday, August 22, 2019

Meaning of life Human Essay Example for Free

Meaning of life Human Essay Youth is not a time of life; it is a state of mind; it is not a matter of rosy cheeks, red lips and supple knees; it is a matter of the will, a quality of the imagination, a vigor of the emotions; it is the freshness of the deep springs of life. Youth means a temperamental predominance of courage over timidity, of the appetite for adventure over the love of ease. This often exists in a man of 60 more than a boy of 20. Nobody grows old merely by a number of years. We grow old by deserting our ideals. Years may wrinkle the skin, but to give up enthusiasm wrinkles the soul. Worry, fear, self-distrust bows the heart and turns the spirit back to dust. Whether 60 or 16, there is in every human being’s heart the lure of wonders, the unfailing appetite for what’s next and the joy of the game of living. In the center of your heart and my heart, there is a wireless station; so long as it receives messages of beauty, hope, courage and power from man and from the infinite, so long as you are young. When your aerials are down, and your spirit is covered with snows of cynicism and the ice of pessimism, then you’ve grown old, even at 20; but as long as your aerials are up, to catch waves of optimism, there’s hope you may die young at 80.  · : Three Days to See(Excerpts) ( ) Three Days to See All of us have read thrilling stories in which the hero had only a limited and specified time to live. Sometimes it was as long as a year, sometimes as short as 24 hours. But always we were interested in discovering just how the doomed hero chose to spend his last days or his last hours. I speak, of course, of free men who have a choice, not condemned criminals whose sphere of activities is strictly delimited. Such stories set us thinking, wondering what we should do under similar circumstances. What events, what experiences, what associations should we crowd into those last hours as mortal beings, what regrets? Sometimes I have thought it would be an excellent rule to live each day as if we should die tomorrow. Such an attitude would emphasize sharply the values of life. We should live each day with gentleness, vigor and a keenness of appreciation which are often lost when time stretches before us in the constant panorama of more days and months and years to come. There are those, of course, who would adopt the Epicurean motto of â€Å"Eat, drink, and be merry†. But most people would be chastened by the certainty of impending death. In stories the doomed hero is usually saved at the last minute by some stroke of fortune, but almost always his sense of values is changed. He becomes more appreciative of the meaning of life and its permanent spiritual values. It has often been noted that those who live, or have lived, in the shadow of death bring a mellow sweetness to everything they do. Most of us, however, take life for granted. We know that one day we must die, but usually we picture that day as far in the future. When we are in buoyant health, death is all but unimaginable. We seldom think of it. The days stretch out in an endless vista. So we go about our petty tasks, hardly aware of our listless attitude toward life. The same lethargy, I am afraid, characterizes the use of all our faculties and senses. Only the deaf appreciate hearing, only the blind realize the manifold blessings that lie in sight. Particularly does this observation apply to those who have lost sight and hearing in adult life. But those who have never suffered impairment of sight or hearing seldom make the fullest use of these blessed faculties. Their eyes and ears take in all sights and sounds hazily, without concentration and with little appreciation. It is the same old story of not being grateful for what we have until we lose it, of not being conscious of health until we are ill. I have often thought it would be a blessing if each human being were stricken blind and deaf for a few days at some time during his early adult life. Darkness would make him more appreciative of sight; silence would teach him the joys of sound.  · :Companionship of Books ( ) Companionship of Books A man may usually be known by the books he reads as well as by the company he keeps; for there is a companionship of books as well as of men; and one should always live in the best company, whether it be of books or of men. A good book may be among the best of friends. It is the same today that it always was, and it will never change. It is the most patient and cheerful of companions. It does not turn its back upon us in times of adversity or distress. It always receives us with the same kindness; amusing and instructing us in youth, and comforting and consoling us in age. Men often discover their affinity to each other by the mutual love they have for a book just as two persons sometimes discover a friend by the admiration which both entertain for a third. There is an old proverb, ‘Love me, love my dog. † But there is more wisdom in this:† Love me, love my book. † The book is a truer and higher bond of union. Men can think, feel, and sympathize with each other through their favorite author. They live in him together, and he in them. A good book is often the best urn of a life enshrining the best that life could think out; for the world of a man’s life is, for the most part, but the world of his thoughts. Thus the best books are treasuries of good words, the golden thoughts, which, remembered and cherished, become our constant companions and comforters. Books possess an essence of immortality. They are by far the most lasting products of human effort. Temples and statues decay, but books survive. Time is of no account with great thoughts, which are as fresh today as when they first passed through their author’s minds, ages ago. What was then said and thought still speaks to us as vividly as ever from the printed page. The only effect of time have been to sift out the bad products; for nothing in literature can long survive e but what is really good. Books introduce us into the best society; they bring us into the presence of the greatest minds that have ever lived. We hear what they said and did; we see the as if they were really alive; we sympathize with them, enjoy with them, grieve with them; their experience becomes ours, and we feel as if we were in a measure actors with them in the scenes which they describe. The great and good do not die, even in this world. Embalmed in books, their spirits walk abroad. The book is a living voice. It is an intellect to which on still listens.  · :If I Rest,I Rust , If I Rest, I Rust The significant inscription found on an old keyâ€Å"If I rest, I rust†would be an excellent motto for those who are afflicted with the slightest bit of idleness. Even the most industrious person might adopt it with advantage to serve as a reminder that, if one allows his faculties to rest, like the iron in the unused key, they will soon show signs of rust and, ultimately, cannot do the work required of them. Those who would attain the heights reached and kept by great men must keep their faculties polished by constant use, so that they may unlock the doors of knowledge, the gate that guard the entrances to the professions, to science, art, literature, agricultureevery department of human endeavor. Industry keeps bright the key that opens the treasury of achievement. If Hugh Miller, after toiling all day in a quarry, had devoted his evenings to rest and recreation, he would never have become a famous geologist. The celebrated mathematician, Edmund Stone, would never have published a mathematical dictionary, never have found the key to science of mathematics, if he had given his spare moments to idleness, had the little Scotch lad, Ferguson, allowed the busy brain to go to sleep while he tended sheep on the hillside instead of calculating the position of the stars by a string of beads, he would never have become a famous astronomer. Labor vanquishes allnot inconstant, spasmodic, or ill-directed labor; but faithful, unremitting, daily effort toward a well-directed purpose. Just as truly as eternal vigilance is the price of liberty, so is eternal industry the price of noble and enduring success.  · :Ambition Ambition It is not difficult to imagine a world short of ambition. It would probably be a kinder world: with out demands, without abrasions, without disappointments. People would have time for reflection. Such work as they did would not be for themselves but for the collectivity. Competition would never enter in. conflict would be eliminated, tension become a thing of the past. The stress of creation would be at an end. Art would no longer be troubling, but purely celebratory in its functions. Longevity would be increased, for fewer people would die of heart attack or stroke caused by tumultuous endeavor. Anxiety would be extinct. Time would stretch on and on, with ambition long departed from the human heart. Ah, how unrelieved boring life would be! There is a strong view that holds that success is a myth, and ambition therefore a sham. Does this mean that success does not really exist? That achievement is at bottom empty? That the efforts of men and women are of no significance alongside the force of movements and events now not all success, obviously, is worth esteeming, nor all ambition worth cultivating. Which are and which are not is something one soon enough learns on one’s own. But even the most cynical secretly admit that success exists; that achievement counts for a great deal; and that the true myth is that the actions of men and women are useless. To believe otherwise is to take on a point of view that is likely to be deranging. It is, in its implications, to remove all motives for competence, interest in attainment, and regard for posterity. We do not choose to be born. We do not choose our parents. We do not choose our historical epoch, the country of our birth, or the immediate circumstances of our upbringing. We do not, most of us, choose to die; nor do we choose the time or conditions of our death. But within all this realm of choicelessness, we do choose how we shall live: courageously or in cowardice, honorably or dishonorably, with purpose or in drift. We decide what is important and what is trivial in life. We decide that what makes us significant is either what we do or what we refuse to do. But no matter how indifferent the universe may be to our choices and decisions, these choices and decisions are ours to make. We decide. We choose. And as we decide and choose, so are our lives formed. In the end, forming our own destiny is what ambition is about.  · :What I have Lived for What I Have Lived For Three passions, simple but overwhelmingly strong, have governed my life: the longing for love, the search for knowledge, and unbearable pity for the suffering of mankind. These passions, like great winds, have blown me hither and thither, in a wayward course, over a deep ocean of anguish, reaching to the very verge of despair. I have sought love, first, because it brings ecstasyecstasy so great that I would often have sacrificed all the rest of my life for a few hours for this joy. I have sought it, next, because it relieves lonelinessthat terrible loneliness in which one shivering consciousness looks over the rim of the world into the cold unfathomable lifeless abyss. I have sought it, finally, because in the union of love I have seen, in a mystic miniature, the prefiguring vision of the heaven that saints and poets have imagined. This is what I sought, and though it might seem too good for human life, this is whatat lastI have found. With equal passion I have sought knowledge. I have wished to understand the hearts of men. I have wished to know why the stars shine. And I have tried to apprehend the Pythagorean power by which number holds sway above the flux. A little of this, but not much, I have achieved. Love and knowledge, so far as they were possible, led upward toward the heavens. But always it brought me back to earth. Echoes of cries of pain reverberate in my heart. Children in famine, victims tortured by oppressors, helpless old people a hated burden to their sons, and the whole world of loneliness, poverty, and pain make a mockery of what human life should be. I long to alleviate the evil, but I cannot, and I too suffer. This has been my life. I have found it worth living, and would gladly live it again if the chance were offered me.  · :When Love Beckons You When Love Beckons You When love beckons to you, follow him, though his ways are hard and steep. And when his wings enfold you, yield to him, though the sword hidden among his pinions may wound you. And when he speaks to you, believe in him, though his voice may shatter your dreams as the north wind lays waste the garden. For even as love crowns you so shall he crucify you. Even as he is for your growth so is he for your pruning. Even as he ascends to your height and caresses your tenderest branches that quiver in the sun, so shall he descend to our roots and shake them in their clinging to the earth. But if, in your fear, you would seek only love’s peace and love’s pleasure, then it is better for you that you cover your nakedness and pass out of love’s threshing-floor, into the seasonless world where you shall laugh, but not all of your laughter, and weep, but not all of your tears. Love gives naught but it self and takes naught but from itself. Love possesses not, nor would it be possessed, for love is sufficient unto love. Love has no other desire but to fulfill itself. But if you love and must have desires, let these be your desires: To melt and be like a running brook that sings its melody to the night. To know the pain of too much tenderness. To be wounded by your own understanding of love; And to bleed willingly and joyfully. To wake at dawn with a winged heart and give thanks for another day of loving; To rest at the noon hour and meditate love’s ecstasy; To return home at eventide with gratitude; And then to sleep with a payer for the beloved in your heart and a song of praise upon your lips.  · :The Road to Success The Road to Success It is well that young men should begin at the beginning and occupy the most subordinate positions. Many of the leading businessmen of Pittsburgh had a serious responsibility thrust upon them at the very threshold of their career. They were introduced to the broom, and spent the first hours of their business lives sweeping out the office. I notice we have janitors and janitresses now in offices, and our young men unfortunately miss that salutary branch of business education. But if by chance the professional sweeper is absent any morning, the boy who has the genius of the future partner in him will not hesitate to try his hand at the broom. It does not hurt the newest comer to sweep out the office if necessary. I was one of those sweepers myself. Assuming that you have all obtained employment and are fairly started, my advice to you is â€Å"aim high†. I would not give a fig for the young man who does not already see himself the partner or the head of an important firm. Do not rest content for a moment in your thoughts as head clerk, or foreman, or general manager in any concern, no matter how extensive. Say to yourself, â€Å"My place is at the top. † Be king in your dreams. And here is the prime condition of success, the great secret: concentrate your energy, thought, and capital exclusively upon the business in which you are engaged. Having begun in one line, resolve to fight it out on that line, to lead in it, adopt every improvement, have the best machinery, and know the most about it. The concerns which fail are those which have scattered their capital, which means that they have scattered their brains also. They have investments in this, or that, or the other, here there, and everywhere. â€Å"Don’t put all your eggs in one basket. † is all wrong. I tell you to â€Å"put all your eggs in one basket, and then watch that basket. † Look round you and take notice, men who do that not often fail. It is easy to watch and carry the one basket. It is trying to carry too many baskets that breaks most eggs in this country. He who carries three baskets must put one on his head, which is apt to tumble and trip him up. One fault of the American businessman is lack of concentration. To summarize what I have said: aim for the highest; never enter a bar room; do not touch liquor, or if at all only at meals; never speculate; never indorse beyond your surplus cash fund; make the firm’s interest yours; break orders always to save owners; concentrate; put all your eggs in one basket, and watch that basket; expenditure always within revenue; lastly, be not impatient, for as Emerson says, â€Å"no one can cheat you out of ultimate success but yourselves. †  · :On Meeting the Celebrated On Meeting the Celebrated I have always wondered at the passion many people have to meet the celebrated. The prestige you acquire by being able to tell your friends that you know famous men proves only that you are yourself of small account. The celebrated develop a technique to deal with the persons they come across. They show the world a mask, often an impressive on, but take care to conceal their real selves. They play the part that is expected from them, and with practice learn to play it very well, but you are stupid if you think that this public performance of theirs corresponds with the man within. I have been attached, deeply attached, to a few people; but I have been interested in men in general not for their own sakes, but for the sake of my work. I have not, as Kant enjoined, regarded each man as an end in himself, but as material that might be useful to me as a writer. I have been more concerned with the obscure than with the famous. They are more often themselves. They have had no need to create a figure to protect themselves from the world or to impress it. Their idiosyncrasies have had more chance to develop in the limited circle of their activity, and since they have never been in the public eye it has never occurred to them that they have anything to conceal. They display their oddities because it has never struck them that they are odd. And after all it is with the common run of men that we writers have to deal; kings, dictators, commercial magnates are from our point of view very unsatisfactory. To write about them is a venture that has often tempted writers, but the failure that has attended their efforts shows that such beings are too exceptional to form a proper ground for a work of art. They cannot be made real. The ordinary is the writer’s richer field. Its unexpectedness, its singularity, its infinite variety afford unending material. The great man is too often all of a piece; it is the little man that is a bundle of contradictory elements. He is inexhaustible. You never come to the end of the surprises he has in store for you. For my part I would much sooner spend a month on a desert island with a veterinary surgeon than with a prime minister.  · :The 50-Percent Theory of Life The 50-Percent Theory of Life I believe in the 50-percent theory. Half the time things are better than normal; the other half, they re worse. I believe life is a pendulum swing. It takes time and experience to understand what normal is, and that gives me the perspective to deal with the surprises of the future. Let’s benchmark the parameters: yes, I will die. I’ve dealt with the deaths of both parents, a best friend, a beloved boss and cherished pets. Some of these deaths have been violent, before my eyes, or slow and agonizing. Bad stuff, and it belongs at the bottom of the scale. Then there are those high points: romance and marriage to the right person; having a child and doing those Dad things like coaching my son’s baseball team, paddling around the creek in the boat while he’s swimming with the dogs, discovering his compassion so deep it manifests even in his kindness to snails, his imagination so vivid he builds a spaceship from a scattered pile of Legos. But there is a vast meadow of life in the middle, where the bad and the good flip-flop acrobatically. This is what convinces me to believe in the 50-percent theory. One spring I planted corn too early in a bottomland so flood-prone that neighbors laughed. I felt chagrined at the wasted effort. Summer turned brutalthe worst heat wave and drought in my lifetime. The air-conditioned died; the well went dry; the marriage ended; the job lost; the money gone. I was living lyrics from a country tunemusic I loathed. Only a surging Kansas City Royals team buoyed my spirits. Looking back on that horrible summer, I soon understood that all succeeding good things merely offset the bad. Worse than normal wouldn’t last long. I am owed and savor the halcyon times. The reinvigorate me for the next nasty surprise and offer assurance that can thrive. The 50-percent theory even helps me see hope beyond my Royals’ recent slump, a field of struggling rookies sown so that some year soon we can reap an October harvest. For that on blistering summer, the ground moisture was just right, planting early allowed pollination before heat withered the tops, and the lack of rain spared the standing corn from floods. That winter my crib overflowed with cornfat, healthy three-to-a-stalk ears filled with kernels from heel to tipwhile my neighbors’ fields yielded only brown, empty husks. Although plantings past may have fallen below the 50-percent expectation, and they probably will again in the future, I am still sustained by the crop that flourishes during the drought.  · :What is Your Recovery Rate? What is Your Recovery Rate? What is your recovery rate? How long does it take you to recover from actions and behaviors that upset you? Minutes? Hours? Days? Weeks? The longer it takes you to recover, the more influence that incident has on your actions, and the less able you are to perform to your personal best. In a nutshell, the longer it takes you to recover, the weaker you are and the poorer your performance. You are well aware that you need to exercise to keep the body fit and, no doubt, accept that a reasonable measure of health is the speed in which your heart and respiratory system recovers after exercise. Likewise the faster you let go of an issue that upsets you, the faster you return to an equilibrium, the healthier you will be. The best example of this behavior is found with professional sportspeople. They know that the faster they can forget an incident or missd opportunity and get on with the game, the better their performance. In fact, most measure the time it takes them to overcome and forget an incident in a game and most reckon a recovery rate of 30 seconds is too long! Imagine yourself to be an actor in a play on the stage. Your aim is to play your part to the best of your ability. You have been given a script and at the end of each sentence is a ful stop. Each time you get to the end of the sentence you start a new one and although the next sentence is related to the last it is not affected by it. Your job is to deliver each sentence to the best of your ability. Don’t live your life in the past! Learn to live in the present, to overcome the past. Stop the past from influencing your daily life. Don’t allow thoughts of the past to reduce your personal best. Stop the past from interfering with your life. Learn to recover quickly. Remember: Rome wasn’t built in a day. Reflect on your recovery rate each day. Every day before you go to bed, look at your progress. Don’t lie in bed saying to you, â€Å"I did that wrong. † â€Å"I should have done better there. † No. look at your day and note when you made an effort to place a full stop after an incident. This is a success. You are taking control of your life. Remember this is a step by step process. This is not a make-over. You are undertaking real change here. Your aim: reduce the time spent in recovery. The way forward? Live in the present. Not in the precedent.  · :Clear Your Mental Space Clear Your Mental Space Think about the last time you felt a negative emotionlike stress, anger, or frustration. What was going through your mind as you were going through that negativity? Was your mind cluttered with thoughts? Or was it paralyzed, unable to think? The next time you find yourself in the middle of a very stressful time, or you feel angry or frustrated, stop. Yes, that’s right, stop. Whatever you’re doing, stop and sit for one minute. While you’re sitting there, completely immerse yourself in the negative emotion. Allow that emotion to consume you. Allow yourself one minute to truly feel that emotion. Don’t cheat yourself here. Take the entire minutebut only one minuteto do nothing else but feel that emotion. When the minute is over, ask yourself, â€Å"Am I wiling to keep holding on to this negative emotion as I go through the rest of the day? † Once you’ve allowed yourself to be totally immersed in the emotion and really fell it, you will be surprised to find that the emotion clears rather quickly. If you feel you need to hold on to the emotion for a little longer, that is OK. Allow yourself another minute to feel the emotion. When you feel you’ve had enough of the emotion, ask yourself if you’re willing to carry that negativity with you for the rest of the day. If not, take a deep breath. As you exhale, release all that negativity with your breath. This exercise seems simplealmost too simple. But, it is very effective. By allowing that negative emotion the space to be truly felt, you are dealing with the emotion rather than stuffing it down and trying not to feel it. You are actually taking away the power of the emotion by giving it the space and attention it needs. When you immerse yourself in the emotion, and realize that it is only emotion, it loses its control. You can clear your head and proceed with your task. Try it. Next time you’re in the middle of a negative emotion, give yourself the space to feel the emotion and see what happens. Keep a piece of paper with you that says the following: Stop. Immerse for one minute. Do I want to keep this negativity? Breath deep, exhale, release. Move on! This will remind you of the steps to the process. Remember; take the time you need to really immerse yourself in the emotion. Then, when you feel you’ve felt it enough, release itreally let go of it. You will be surprised at how quickly you can move on from a negative situation and get to what you really want to do!  · :Be Happy Be Happy! â€Å"The days that make us happy make us wise. †-John Masefield when I first read this line by England’s Poet Laureate, it startled me. What did Masefield mean? Without thinking about it much, I had always assumed that the opposite was true. But his sober assurance was arresting. I could not forget it. Finally, I seemed to grasp his meaning and realized that here was a profound observation. The wisdom that happiness makes possible lies in clear perception, not fogged by anxiety nor dimmed by despair and boredom, and without the blind spots caused by fear. Active happinessnot mere satisfaction or contentment often comes suddenly, like an April shower or the unfolding of a bud. Then you discover what kind of wisdom has accompanied it. The grass is greener; bird songs are sweeter; the shortcomings of your friends are more understandable and more forgivable. Happiness is like a pair of eyeglasses correcting your spiritual vision. Nor are the insights of happiness limited to what is near around you. Unhappy, with your thoughts turned in upon your emotional woes, your vision is cut short as though by a wall. Happy, the wall crumbles. The long vista is there for the seeing. The ground at your feet, the world about you-people, thoughts, emotions, pressuresare now fitted into the larger scene. Everything assumes a fairer proportion. And here is the beginning of wisdom.  · :The Goodness of life The Goodness of Life Though there is much to be concerned about, there is far, far more for which to be thankful. Though life’s goodness can at times be overshadowed, it is never outweighed. For every single act that is senselessly destructive, there are thousands more small, quiet acts of love, kindness and compassion. For every person who seeks to hurt, there are many, many more who devote their lives to helping and to healing. There is goodness to life that cannot be denied. In the most magnificent vistas and in the smallest details, look closely, for that goodness always comes shining through. There si no limit to the goodness of life. It grows more abundant with each new encounter. The more you experience and appreciate the goodness of life, the more there is to be lived. Even when the cold winds blow and the world seems to be cov ered in foggy shadows, the goodness of life lives on. Open your eyes, open your heart, and you will see that goodness is everywhere. Though the goodness of life seems at times to suffer setbacks, it always endures. For in the darkest moment it becomes vividly clear that life is a priceless treasure. And so the goodness of life is made even stronger by the very things that would oppose it. Time and time again when you feared it was gone forever you found that the goodness of life was really only a moment away. Around the next corner, inside every moment, the goodness of life is there to surprise and delight you. Take a moment to let the goodness of life touch your spirit and calm your thoughts. Then, share your good fortune with another. For the goodness of life grows more and more magnificent each time it is given away. Though the problems constantly scream for attention and the conflicts appear to rage ever stronger, the goodness of life grows stronger still, quietly, peacefully, with more purpose and meaning than ever before.  · :Facing the Enemies Within Facing the Enemies Within We are not born with courage, but neither are we born with fear. Maybe some of our fears are brought on by your own experiences, by what someone has told you, by what you’ve read in the papers. Some fears are valid, like walking alone in a bad part of town at two o’clock in the morning. But once you learn to avoid that situation, you won’t need to live in fear of it. Fears, even the most basic ones, can totally destroy our ambitions. Fear can destroy fortunes. Fear can destroy relationships. Fear, if left unchecked, can destroy our lives. Fear is one of the many enemies lurking inside us. Let me tell you about five of the other enemies we face from within. The first enemy that you’ve got to destroy before it destroys you is indifference. What a tragic disease this is! â€Å"Ho-hum, let it slide. I’ll just drift along. † Here’s one problem with drifting: you can’t drift your way to the to of the mountain. The second enemy we face is indecision. Indecision is the thief of opportunity and enterprise. It will steal your chances for a better future. Take a sword to this enemy. The third enemy inside is doubt. Sure, there’s room for healthy skepticism. You can’t believe everything. But you also can’t let doubt take over. Many people doubt the past, doubt the future, doubt each other, doubt the government, doubt the possibilities nad doubt the opportunities. Worse of all, they doubt themselves. I’m telling you, doubt will destroy your life and your chances of success. It will empty both your bank account and your heart. Doubt is an enemy. Go after it. Get rid of it. The fourth enemy within is worry. We’ve all got to worry some. Just don’t let conquer you. Instead, let it alarm you. Worry can be useful. If you step off the curb in New York City and a taxi is coming, you’ve.

Wednesday, August 21, 2019

Dipole Moment of 5- Fluorouracil Molecule

Dipole Moment of 5- Fluorouracil Molecule Computational Term Paper: Theoretical studies on 5- fluorouracil to calculate its dipole moment, and how the values compare with other pyrimidine analog (namely uracil and thymine) and that of literature. Name: Farzana Nushin Rezvi Abstract: In this experiment, the dipole moment of 5- Fluorouracil molecule was determined using the Gaussian software, and compared with literature values. The dipole moments of other pyrimidine analogs, namely Thymine and Uracil, were also calculated and compared with literature values. The experiment gave insight to typical dipole moment values of uracil derivatives, and how the dipole moment of aromatic molecules can be influenced in the presence of –F, or -CH3 substituent. Introduction: The purpose of this experiment is to calculate the dipole moment of the anticancer drug, 5- Fluorouracil, and compare the numerical value with that of two other pyrimidines, Thymine and Uracil. Fig 1: Molecular structure of 5- Fluoro uracil (drawn by ChemBioDraw). 5- Fluorouracil is apyrimidine analog (nucleoside analogs that mimic the molecular structure of pyrimidines) of uracil molecule that functions as an anti-cancer drug; it is used in the treatment of several types of cancer, including that of rectum, colon, head and neck cancer.10 5- Fluorouracil belongs to the family of drugs called theantimetabolites. Antimetabolite drugs function by impeding vital biosynthetic processes or by being assimilated into macromolecules, and inhibiting their normal functioning. The fluoro pyrimidine drug, 5-fluorouracil (5-FU) does both.9Cancer cells often use more uracil than normal cells, which indicates that uracil metabolism is a potential target for antimetabolite chemotherapy.9 â€Å"The mechanism of cytotoxicity of 5-FU has been ascribed to the misincorporation of fluoronucleotides into RNA and DNA and to the inhibition of the nucleotide synthetic enzyme thymidylate synthase.†9 Thymidylate synthase is an enzyme that catalyzes the conversion o f deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP). dTMP is one of the three nucleotides (dTMP, dTTP, and dTDP) that eventually produce a thymine molecule. With inhibition of Thymidylate synthase, an imbalance of nucleotides results and increased levels of dUTP arise. Both of these factors cause DNA damage, therefore ultimately inhibiting cell replication. 5 FU is also seldom found in skin creams used for other conditions. However, it should be used in moderate/regulated amounts since the side effects of unregulated exposure can be severe.10 5-Fluorouracil is a derivative of Uracil. Another structural analog of Uracil is Thymine. As can be seen from the figure below, the molecules only differ in what substituent each has on C-5. Fig 2: Molecular structures of Uracil, 5-Fluorouracil, and Thymine. Thymine is one of the four nucleobases of DNA. Uracil is the RNA analogue of Thymine. Unlike Fluorouracil, these bases are regularly used by a healthy cell to construct new nucleotides (for multiplication, repair, etc.) The dipole moment is considered to be an elementary physiochemical property of a molecule. Interpretation of dipole moments by electronic charge distribution contributes to the understanding the molecular electronic structure and helps us gain deeper insight. The numerical values of the dipole moments also help us in evaluating the quantum mechanical calculations of electronic charge distribution, particularly in a series of homologous compounds, as in our experiment. Our experiment helps us understand the effects of substituents at C5 dipole moment of uracil. The dipole moment is a of these three molecules is an interesting study because in each case, the dipole moment is primarily influenced by the presence of electronegative atoms. The dipole moment of a molecule influences many of its properties and features (such as its colligtaive properties, how it interacts with other molecules, its behavior in compounds, etc.) In the molecules under consideration, the dipole moment(s) work as in the following figure (the dipole moment of uracil directed inbetween N3 and C4, with the substituent ‘X’ either strengthening, or weakening the dipole in the illustrated vectors)6: Fig 3: Vector scheme of dipole moments in uracil and in its derivatives6 (reproduced using ChemBioDraw) Experimental: For this Lab, the Gaussian software was used in calculating the dipole moment. At first, the molecule of concern was drawn using the software. Then ‘Edit’ option is selected to ‘Symmetrize’ our subject molecule. After that is done, we perform Gaussian Calculation Setup, by selecting Job Type as ‘Energy’, and under Methods changing the Basis set. The numerical value of the dipole moment is obtained from the ‘Results’ of the .chk file. The Gaussian calculation is repeated by selecting other Basis sets. The whole process is repeated for the molecules Thymine and Uracil. The molecule is drawn using Gaussian, and the Gaussian calculations repeated by selecting different ‘job types’ and ‘basis sets’. Results: The results obtained are represented in tabular form. The screenshots of the molecules as drawn in the Gaussian software are also given. Tables: Table 1: The theoretical and Literature values of 5-Fluorouracil dipole moment Table 2: The theoretical and Literature values of Uracil dipole moment Table 3: The theoretical and Literature values of Thymine dipole moment. Images obtained from Gaussian: 5-Fluorouracil Fig 4: Image of 5-Fluorouracil molecule as drawn using Gaussian software Uracil: Fig 5: Image of uracil molecule as drawn using Gaussian software Thymine: Fig 6: Image of thymine molecule as drawn using Gaussian software Discussion: The purpose of this experiment was to calculate the numerical values of dipole moments of the anticancer drug, 5- fluorouracil, and two other pyrimidines, thymine and uracil, and compare the obtained values with that of literature values. The dipole moment of a bond is defined as the mathematical product of the magnitude of the charges and distance between atoms under consideration11. The numerical value of the dipole moment can be calculated for each bond, as well as for the entire molecule. In this experiment, we use the Gaussian software for the calculation of dipole moments. The calculation of dipole moment is based on the allocation of atomic charges to the atoms in the molecule in a reasonable way.4 In the hands on experiment, this consists of assigning electronegativity values to the atoms and experimental structural information of the bonds. Topological methods, however, do not take in information about the molecular geometry or the conformational status of the molecule. The topological method currently in use is the Gasteiger-Hà ¼ckelmethod, which has the disadvantage of omitting the validation procedure. This renders the study impractical.11 The method of computation of partial charges employed in this experiment is based on the quantum mechanical calculation of wavefunction.11 For this report, wavefunctions were obtained using the ab initio method. Ab initio means based on first principles, these methods are based on quantum mechanics and attempt to solve the Schrà ¶dinger equation. â€Å"Ab initio methods use no experimental parameters in their calculations, although they use some mathematical approximations. The major disadvantage of Ab Initio quantum chemistry is the heavy demands on computer power.†12 The choice of basis set is one of the most important aspects of this computation, as our results depend vastly on the basis set employed. Basis sets are quantum chemical units of energy; basis set contains mathematical functions that can be used to determine the dipole moment, energy, and other quantum mechanical properties of an atom/molecule of study. Basis sets are considered to represent the wavefunctions of the electrons in the species.12 On the basis of atomic point charges, a molecular dipole moment can be calculated in a quite simple and fast way, and compared with literature values. To get reliable results using this method, one must select small and rigid structures.11 As the dipole moment is a property defined by quantum mechanics, wavefunctions can be used to directly calculate its values. Results derived with large basis sets (such as those reported in this paper) are in good agreement with experimental values. As we can see, our calculated values of the dipole moment align quite closely with the experimental values. One fact, however, stands out: the values of dipole moment get closer to the ‘literature values’ as the basis set is increased. However, quantum mechanical methods are not very useful when obtaining information about larger molecules.11 The dipole moments of uracil, as well as of its respective derivatives are listed in Table 1, Table 2 and Table 3. First of all, it can be noticed that all these molecules have pretty high values for dipole moments, compared to other aromatic molecules.4 This increase seems to be mainly due to the large electronegativity of the O atoms (resulting in large numerical values of the dipole moments of carbonyl groups) which amount to 4 Debye units in thiouracils, according to Schneider and Halverstadt 13 This value can be contributed to the relatively high polarity of the secondary amide carbonyl group in these compounds, as compared with the generally observed value of 2.23 Debye units.4 A pronounced change in the dipole moment is observed only upon the introduction of a substituent of a different polarity, such as Fluorine and Methyl group. In order to examine the effects of substituent on C5 on the electronic charge distribution in greater detail, many factors have to be taken into consideration. The first is that of electronegativity. Halogens are famously electronegative, with F atom being the most. The electronegativity of Fluorine atom pulls away electrons towards itself (and away from the ring) (Refer to Fig 3). As the dipole moment direction of –F atom is directed towards itself, it somewhat cancels the dipole moment of N3. This explains why 5-Fluorouracil has a lower overall dipole moment compared to uracil. Thymine differs from uracil in having a methyl group (-CH3) on C5. The main chemistry to understand here is that of the inductive and mesomeric effect. â€Å"Methylation at C5 and C6 mainly causes changes in the polarity of the C5C6 bond by way of increasing the ~-electronic charge on the atom at which substitution takes place.†6 Due to the positive inductive effect of the –CH3 group, electrons are pushed towards the aromatic ring. This adds to the ‘electron pull’ of N3 and contributes to the overall polarity of the molecule. It can be noted that substitution at C5 does not alter the dipole moment of uracil as much as a substituent on C6 would. (Since the substituents at C5 and C6 are differently oriented). For uracil, the dipole moment is directed in the N atom inbetween the carbonyl groups (as shown in Fig 3). However, the dipole moment is a more complicated calculation than can be inferred from a diagram as simple, lots of other data (such as bond angles) also have to be taken into account. Conclusion: The purpose of this experiment is to calculate the dipole moment of the anticancer drug, 5- fluorouracil, and compare its value with that of literature, and two other pyrimidines, thymine and uracil. Based on the data obtained with 5 FU, the experiment can be deemed to be successful, as it contains about 1-2 % error with respect to literature. In summary, we have demonstrated that these Gaussian calculations is an easy and convenient way to determine many physical and spectroscopic properties of these molecules in solution and can give an additional insight into their in vivo properties.1 Citations: Theoretical DFT and experimental NMR studies on uracil and 5- fluorouracil , B. Blicharska, T. Kupka / Journal of Molecular Structure 613 (2002) 153–166 Frisch, M. J.et al. Gaussian Development Version, Revision D.02. In Gaussian Development Version, Revision D.02; Gaussian, Inc.: Wallingford CT, 2005 5-Fluorouracil and thymine form a crystalline solid solution, Sarah A. Barnett, Ashley T. Hulme* and Derek A. Tocher, Acta Crystallographica Section CVolume 62, Issue 7, Article first published online: 10 JUL 2006 L.A. Curtiss, M.S. Gordon Computational Material Chemistry: Methods and Applications, Kluwer Academic Publishers, 2004 Structures of the Molecular Components in DNA and RNA with Bond Lengths Interpreted as Sums of Atomic Covalent Radii Institute of Biophysics of the Academy of Sciences of the Czech Republic, Krà ¡lovopolskà ¡ 135, 61265 Brno, Czech Republic. Dipole moments of 2,4-diketopyrimidines: Part II: Uracil, thymine and their derivatives I. Kulakowskaa, M. Gellerb, B. Lesyngb, K.L. Wierzchowskia, Biochimica et Biophysica Acta (BBA) Nucleic Acids and Protein Synthesis Volume 361, Issue 2, 29 August 1974, Pages 119–130 Chapter chemotherapy cancer http://www.oncoprof.net/Generale2000/g09_Chimiotherapie/Complements/g09_comp11.php (accessed Nov 19, 2014) Cole Parmer http://www.coleparmer.com/Product/5_Fluorouracil_99_5g/EW-88244-97 (accessed Nov 19, 2014) 5-Fluorouracil: mechanisms of action and clinical strategies, Daniel B. Longley1, D. Paul Harkin1 Patrick G. Johnston, Nature Reviews Cancer 3, 330-338 (May 2003) Wikipedia http://en.wikipedia.org/wiki/Fluorouracil (accessed 3rd December 2014) Hans-Dieter Hà ¶ltje, Gerd Folker, Molecular Modeling: Basic Principles and Applications, VCH Publishers, 1997 Vol. 5 Samakhvalov A, Lab Manual for Physical Chemistry I, Rutgers University Camden 2014 Schneider, W.C. and Halverstadt, I.F. (1948) J. Am. Chem. Soc. 70, 262626 1

Tuesday, August 20, 2019

Dawn Bread Company Analysis

Dawn Bread Company Analysis Company Profile Dawn Bread Dawn Bread is amongst the leading bakers of the world, and are committed to constantly upgrading quality, health standards and nutritional values. Dawn Bread have brought one of the worlds most technologically advanced baking units to Pakistan and the use of quality ingredients and an advanced production process ensure that its consumers have purchased a fresh and wholesome product of world class standard. Dawn Breada name that has come to signify quality and freshness in bread products. A success story that was written by a family that is committed to honest to goodness enterprise and concerned with the prosperity of the country. The enterprise, which made a humble beginning in late 1981, has, within a decade, grown to capture 35% of the consolidated market share of all bread products in the country, a fact that speaks volumes about the credibility of the company and its products. Prior to the establishment of Dawn Bread, the largest producer of bread products was the public sector. However, this sector could not cope with the demands of the consumer and this when, perceiving a change in the eating habits of Pakistanis, Dawn Bread was envisioned. Beginning with the plant in Karachi, commissioned in October 1981, Dawn Bread built-up a reputation for freshness, quality and taste. Creating awareness plus a demand for bread products, the second plant was commissioned in Islamabad in January 1985. Nothing succeeds like success, so next came the plant in Hyderabad in January 1987, a year that was to also witness the establishment of another plant at Lahore, in November 1987. In 1989 we established the plant at Multan. After consolidating this expansion, the sixth plant was commissioned at Faisalabad in February 1992. Now our customers can find Dawns quality and freshness from the southern tip of Pakistan to the Northern city of Peshawar. For purpose of standardization, the company associated itself with FMBRA of United Kingdom in 1990 to bring itself in line with international standards of production, technology, machinery and formulation Now, all theDawn Breadplants boast of the latest machinery used in the bread-making process. They are managed by senior food technologists with decades of experience, while those manning the machinery are provided on the job training in congenial working conditions. Taking a responsible place in society, the company is committed to the uplift and development of the society as a whole, and participates in sports and social welfare activities. Products of Dawn Bread Dawn Bread is amongst the leading bakers of the Pakistan, and is committed to constantly upgrading quality, health standards and nutritional values. Dawn Bread have brought one of the worlds most technologically advanced baking units to Pakistan and the use of quality ingredients and an advanced production process ensure that its consumers have purchased a fresh and wholesome product of world class standard. Dawn Bread has good range of products mainly categorized into Breads, Buns, Sweets, Frozen and other. Following is the description of products of Dawn Bread: Breads Product Description Multigrain Dawns Multigrain bread brings you Natures Best in a perfectly soft, grainy and textured loaf . Baked from a special combination of imported grains, full of natural flavor aroma, this premium bread is a perfect companion to any meal, snack, sandwich or just by itself. Fresh Wholesome Goodness for the whole family to enjoy! Bran Bread Dawns Bran Bread freshly baked for health conscious customers. This bread contributes towards the daily intake of fiber to help maintain the right balanced diet. Milky Bread Made by the addition of milk, this oven fresh aromatic bread is made so that each slice contains the richest of texture and gives that extra taste. Plain White Bread This freshly baked and nutritious bread was one of the first products to be introduced in the Pakistani market by Dawn Bread. Fortified Bread Freshly baked and wholesome, this bread contributes to the recommended daily intake of essential nutrients that form a major component of a healthy and balanced diet. Made from the finest ingredients, this multi purpose bread can be used for breakfast, lunch, dinner, snacks or whenever, with whatever you like. Buns Product Description Hot Dog Buns Hot Dog Buns are growing in popularity by the day. Baked using the strictest of quality standards, our tasty product is made to be the freshest hot dog bun available in the Pakistani market. Fruity Buns An all time favorite breakfast alternative commonly known as Maska Bun, our Fruit bun still carries that distinct taste perfected by Dawn. Served with a luxuriant layer of butter or just by itself, the taste of this sweet treat will not let you down. Burger Buns Our Oven fresh buns are a treat by themselves. Baked by using only the very finest of ingredients, and perfected by years of experience in the baking field, these aromatic buns make the perfect burgers. We also take pride in the fact that we are the official bakers in Pakistan for the largest fast food chain in the world Sweets Product Description Strawberry Vanila Cake Strawberry Vanila flavored cakes made with only the best of ingredients. These little delights are simply a must have, good things do come in small packages. Short Cake Sometime called Ship Cake, is best choice for tea parties and snacks. One of the most popular products of Dawn Bread in Cake category. Pineapple Cake Cup Shaped cake flavored with pineapple and with only the best of ingredients. Mango Cake Mango Cake is tasty cup shaped cake full of mango flavor, best in all seasons. Fresh and likeable product of Dawn Bread Cup Cake Simple tasty cup shaped cakes made with only the best of ingredients. Frozen Product Description DAWN PARATHA FROZEN PARATHA PREPARED ON PLANT In line with Dawns philosophy of continues innovation, we are proud to be the first to introduce DAWNs PARATHA. Our paratha provides the best of both worlds, giving the same home cooked tasted while providing the most convenient preparation method possible. Other Product Description DAWN RUSK The first packaged crispy rusks to be made available in the Pakistani market. Made under hygienic conditions and packaged to retain their freshness and taste. Try our rusk with tea or coffee today. Export Products of Dawn Bread Dawn Bread also has number of export food products under category of Frozen Dough of different type with tag name Mezban. Dawn Bread amongst the leading bakers of the world, and are committed to constantly upgrading quality, health standards and nutritional values. Dawn Bread use of quality ingredients and an advanced production process ensure that its consumers have purchased a fresh and wholesome product of world class standard. Export Products and Description Aloo Paratha Griddle-fried Potato stuffed flat breads are called Aloo Parathas The stuffing is made with mouth watering exotic potatos prepared with different herbs and spices. For a simple, rich indulgence eat it plain or top a freshly made hot parantha with a dollop of whipped butter or mint chutney. Enjoy! Sheermal Sheermal is a sweet flat bread baked in clay ovens which gives it a unique aroma and texture.It can be eaten plain or with any curry of your choice. Enjoy! Puri Puri is a thin flat bread which after deep frying turns into a crispy golden brown bread. Puri can be served with pickles, spicy potato and chickpee curry or any other meal of your choice Enjoy! Chatpata Mix Vegetable Samosa Mix vegetable samosa is a traditional Pakistani savory pastry stuffed with spicy vegetables.This aromatic appetizer is a perfect harmony of flavor and texture. Stuffed with Potatoes, Peas, Cauliflower,Coriander and a wonderful mix of spices, these samosas are an exotic finger food choice for any occasion. Chatpata Potato Samosa Potato samosa is a traditional Pakistani savory pastry stuffed with spicy mashed potatoes. This aromatic appetizer is a perfect harmony of flavor and texture. Stuffed with potatos, Onions and wonderful spices, these samosas are an exotic finger food choice for any occasion. Chai Paratha Capture the spirit and essence of the Peshawari Chai Paratha as made by Pathan dhabas (cafà ©s) all over. This regional delicacy has been prepared as per the original recipe using only the very finest of ingredients to give you an authentic mouthwatering experience. The original aroma and taste! Takes only minutes to serve!!! Whole Wheat Paratha Regular consumption of fiber is associated with risk reduction of coronary heart disease. In general, soluble fiber (of which oats are a good source) is the dietary fiber most linked to a reduction of cholesterol levels. Dawns Whole Wheat Paratha is prepared with the finest of whole wheat flour, oat bran and margarine to give you the same great tasting paratha, but better suited to a healthy lifestyle. Roghni Kulcha The Kulcha is a traditional unleavened whole wheat bread baked in a clay tandoor (Oven). The distinct smoky flavour of the Kulcha is the result of the moisture dripping onto the hot charcoal in a traditional tandoor. The Naan is pressed against the sides of the pot with the use of a small pillow and is cooked by conducted heat. Incidentally, the familiar tear shape of Naan bread comes from the dough dripping down the sides of the tandoor. Good with any dish bring the tandoor to your table today. Tandoori Roti Tandoori Roti all time best choice for dinner and lunch. Tafan Frozen Taftan product of Dawn Bread with all best ingredients for traditional lunch and dinner. Dawn Bread Product Ingredient Chart Sheet Dawn Bread use quality ingredients and an advanced production process to ensure that its consumers have purchased a fresh and wholesome product of world class standard. Dawn Bread Product Distribution Network in Pakistan Dawn groupsdistribution network comprises of over two hundred company owned vehicles in a distribution system spread all over Pakistan. On a daily basis, Dawn Bread distributes its goods to over a 10,000 retail outlets. This makes Dawn Bread one of the largest distribution networks for any product in Pakistan. Dawn Bread distribute in almost all the major metropolitan areas, secondary metropolitan areas as well as the rural parts of the country. Dawn Bread network has been in the business of touching each of our 10,000 retail customers on a daily basis for the past twenty years. Distribution Network of Dawn Bread in Pakistan can be studied by dividing it into five parts based on its five plants in Pakistan at Karachi, Hyderabad, Faisalabad, Lahore and Rawalpindi in Sindh and Punjab province of Pakistan, respectively as shown in diagram. Plant-wise Distribution Areas of Dawn Bread Dawn Bread Export Product Distribution Network Dawn Bread exports its quality products to different countries of the world namely Alaska, Canada, United States of America, Norway, United Kingdom, Switzerland, Netherlands, Germany, South Africa, Saudia Arabia, Japan as shown in below diagram of Dawn Bread world wide distribution network. In United States of America, distribution network future break down into distribution areas as follow  · Washington  · Oregon  · Idaho  · Nevada  · California  · Texas  · Oklahoma  · Illinois  · Wisconsin  · Michigan  · Indiana  · Ohio  · Virginia  · New York  · Massachusetts  · Connecticut  · New Jersey . Maryland

Monday, August 19, 2019

Social System in Gabriel Marquez’s Chronicle of a Death Foretold and Al

Social System in Gabriel Marquez’s Chronicle of a Death Foretold and Albert Camus’s The Stranger â€Å"Like father, like son† the old saying goes. And naturally this is so, for if the parent lacks morals, logically the child will too. Just as parents shape their children, authority figures shape their societies. Authority figures have great impact on the common people, for if they act in dishonest or fraudulent manners, the society considers it acceptable to do the same. Such reflections between authority figures and society are seen throughout Gabriel Marquez’s Chronicle of a Death Foretold and Albert Camus’s The Stranger. With societies constantly looking to authority figures for guidance, Marquez and Camus satirically depict folly in the actions of the leaders in order to criticize the social system and reveal the accepted selfishness that is reflected by the people. In order to completely understand the manner in which authority figures actions become reflected on society, a reader must observe the social system through the eyes of the narrator. Marquez begins Chronicle of A Death Foretold by establishing the town to appear very religious. The novel commences with the townspeople thoroughly preparing for the yearly arrival of the bishop. The whole town arranges for his arrival, bringing him many gifts and animals. Although Marquez establishes the city as consumed in religious dedication, a reader must analyze the thoughts of the townspeople in order to truly understand the society. The individuals of the community make elaborate preparations, not to show their spiritual devotion, but to benefit their personal selves. Each person concerns themselves with receiving a blessing from the bishop. The people seem to be... ...ngs in order to expunge their sins, The Stranger also presents faith as a means to obliterate sins. In both systems, people rely on religion in hypocritical manners. Instead of desiring a spiritual peace, the people have been taught by authority figures, like the magistrate, to use religion in self-interest. Overall, Marquez and Camus break the spiritual, rational, and impartial facades of the authority figures by exposing the idea that; since the leaders of the society were unable to provide a moral structure for their citizens, an accepted form of selfishness unfolded within the societies. The social systems in both novels act as the shadow of the bishop and the magistrate. Like a shadow, the societies follow in the leaders footsteps, for the society lives as a dark reflection of the authority figures who promote selfishness and false public images.

Sunday, August 18, 2019

Goo Earth :: essays research papers

#  Ã‚  Ã‚  Ã‚  Ã‚  Quotes/Responses  Ã‚  Ã‚  Ã‚  Ã‚  Page # 1  Ã‚  Ã‚  Ã‚  Ã‚  Ã¢â‚¬Å"There was a woman coming to the house. Never again would Wang Lung have to rise†¦at dawn to light the fire. He could lie in his bed and wait.  Ã‚  Ã‚  Ã‚  Ã‚  2   Ã‚  Ã‚  Ã‚  Ã‚  This quote shows the reader the kind of role the woman was supposed to have in her family. She was to do all of the housework, cooking†¦ Basically she takes care of the man’s every need.  Ã‚  Ã‚  Ã‚  Ã‚   2  Ã‚  Ã‚  Ã‚  Ã‚  Ã¢â‚¬Å"‘Come here, slave,’ said the old lady carelessly. ‘This man has come for you.’†Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  13   Ã‚  Ã‚  Ã‚  Ã‚  Female children were often sold as slaves to rich families. This wasn’t done with male children, which shows that the male children were held in much higher regards, and that they were worth more to a family.  Ã‚  Ã‚  Ã‚  Ã‚   3  Ã‚  Ã‚  Ã‚  Ã‚  Ã¢â‚¬Å"‘Is it a man?’ he cried importunely.†Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  27   Ã‚  Ã‚  Ã‚  Ã‚  Male children were wanted more than females because they could own land and grow crops, something that the government prohibited females to do.  Ã‚  Ã‚  Ã‚  Ã‚   4  Ã‚  Ã‚  Ã‚  Ã‚  Ã¢â‚¬Å"‘It is over once more. It is only a slave this time-not worth mentioning.’ Wang lung stood still. A sense of evil struck him. A girl!†Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  46   Ã‚  Ã‚  Ã‚  Ã‚  Wang Lung wasn’t any exception to the rule with girl children. He just wanted to have male children because girls just caused a whole lot of trouble in his eyes.  Ã‚  Ã‚  Ã‚  Ã‚   5  Ã‚  Ã‚  Ã‚  Ã‚  Ã¢â‚¬Å"I would sell this girl for you-to take you back to the land.’†Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  83   Ã‚  Ã‚  Ã‚  Ã‚  O’lan was willing to sell her daughter so that her family could go back to their home and their land. Wang Lung did not think that it was right to do so. O’lan thought that it was ok because she was sold into slavery when her parents needed money  Ã‚  Ã‚  Ã‚  Ã‚   6  Ã‚  Ã‚  Ã‚  Ã‚  Ã¢â‚¬Å"‘My mother did not bind them, since I was sold so young. But the girls' feet I will bind-the younger girl's feet I will bind.’†Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  122   Ã‚  Ã‚  Ã‚  Ã‚  The women were expected to have their feet bound to make them smaller and more beautiful. The women were expected to go through a lot of pain to be presentable to their husband.  Ã‚  Ã‚  Ã‚  Ã‚   7  Ã‚  Ã‚  Ã‚  Ã‚  Ã¢â‚¬Å"‘He chose one most beautiful, a small, slender thing, a body light as a bamboo and a little face as pointed as a kitten's face, and one hand clasping the stem of a lotus flower in bud, and the hand as delicate as the tendril of a fern uncurled.’†Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  126   Ã‚  Ã‚  Ã‚  Ã‚  This quote refers to Wang Lung when he went to pay for his pleasures with a beautiful woman. This kind of thing was ok for a man to do. He could have as many women as he wanted, but a woman could not do the same.

Saturday, August 17, 2019

Nonprofit organizations Essay

TASC which stands for treatment alternative for safe communities is nonprofit making organization providing access to recovery and specialized services for people involved in corrections, criminal justice, public aid systems and child welfare. TASCS programs serve more than 30,000 people each year across Illinois every year including transitional programs for providing management for clinical case to over 4,000 adults each year who enter the community after incarceration. TASC work together with other service providers and partners to offer treatment, support recovery and establish faith –based organization. Addiction treatment field has grown in the past three decades due to expansion of market for illicit drugs in United States which started in 1960s and need for treatment services and intervention. In the areas of societal changes, key leaders have provided guidance on development in the last thirty years. They have shown their understanding on the need and possibilities for the field, they assess environmental landscape in order to anticipate the coming trends, take care of appropriate risks, act collectively in advancing the field and use influence and power in achieving a common vision. New leaders have been developed who are involved in identification and possible growth of individual who will be leaders of the field of alcohol, prevention and treatment of drugs in the years to come. Beyond leadership being understood as competencies and individual skills, cultures need to be developed about leadership at all levels in the organization. Leadership is involved in working together with others to advance the overall field. It explores, define and implement strategies to bring together diverse entities under common purposes and goals. There is a framework for developing leaders by convening efforts such as initiative for partners’ recovery. the main goals of efforts that are made in development of leadership is to make sure there is continuing evolution in leadership and having sound public policy and quality services to everyone. Fragmentation of philosophies has marked the field of preventing substance abuse and treatment of addiction for more than one century. Right now views are different concerning standardizing treatment methods, using medication-assisted treatment, purpose of recovery movement and outcome measures. Instead of a unified voice being presented, the field is described as multiple movements with many leaders and institutions having different agendas. Recently, the field is coming together with common philosophies to understand the science of recovery from addiction. Leadership understands societal context where the field is located. Plan for future of addiction treatment begin by assessing current environment and anticipating forces and trends for shaping the years to come. Forces in the society are external to control of the field yet for the people who will be involved in treatment and recovery; their future will be shaped by the people within the field by understanding opportunities and challenges that may emerge. The skills for a leader in treating addiction are complex. They need understanding of clinical and all service aspects and have business skills such as property acquisition, financing, contracting and managing profit and nonprofit organizations for organization to be viable and competitive. Leadership is involved in being capable of moving others forward to achieve strategic vision and his skills are strategic planning, financial development, mentoring and communication. Management is involved in putting in place all infrastructure and processes for effective working of organization. Vital management and business skills include team building, development of product and service, human resource development and marketing.

Issues in International Economics Essay

Introduction. Correct choice and application of marketing strategies can be regarded as one of the main keys to the success of the company. However, this task becomes particularly challenging nowadays, when the markets are characterized by severe volatility and companies are forced to function in a rapidly changing environment. As the centres of power and influence shift from one parts of the world to others, it is very important for the management of multinational corporations to expand their activities accordingly and ensure their presence in the new territories which offer the best business opportunities. Top European and American corporations have noticed long ago that home markets did not give them sufficient opportunities for growth, and started expanding to those countries which offered them possibilities to obtain large revenues in future. UK’s top supermarket Tesco regards international expansion as one of key determinants of its success in the world market. In this investigation it is expected to provide recommendations for the development of Tesco’s international strategy. The paper seeks to address this question by hypothesizing that China needs to become the key international destination for Tesco and the company’s current state enables it to get well-positioned in China’s retailing market in the following years. Primary attention is devoted to the determination of marketing mix components for Tesco in the new market and development of efficient methods of further marketing research. Characteristics of Tesco’s International Strategy. Tesco is one of the largest players among supermarket retailers in the UK. The range of services which the supermarket offers is literally unlimited. Tesco offers both food and non-food products, according clothing, electric appliances, entertainment goods and many other items. The managers of the store are sure that the large variety of products offered to the customers ensures the increasing profitability of the company. Tesco operates both in the international and in the home market. Tesco has expanded in twelve countries, including Poland, Hungary, the Czech Republic, Slovakia, Thailand, Malaysia and others. Even though its share in relatively small in the international market, it has been growing during the last years. Tesco’s major competitors in the world market are Wal-Mart, Target, Carrefour and others. One of the major current competitors which Tesco has in the domestic market is Sainsbury because it is ranked second by the market share in the UK. Due to the efficient allocation of resources, Tesco has won the battle for the market share. â€Å"TESCO has won the store wars, toppling Sainsbury’s from the number one spot after 10 years. The supermarket rang up pounds 13. 8 billion last year putting it pounds 400 million ahead of Sainsbury’s. † (Kevan 1998: 2). The reason of this victory can be found in efficient pricing and consumer-oriented strategy applied by the company. Tesco managers combined high quality of products which attracts customers with relevant prices, and this increased the sales. Besides, innovation schemes have been applied by Tesco managers. Another reason of Tesco growing profitability is the quality of its human resources. The strategy of Tesco recruitment consists in employing people with great skills and high potential and providing very favourable working conditions for them. One of the recent innovations applied by the management include profit-share schemes which enable employees to participate in the profits of the company. â€Å"The company’s profit-share scheme, which is now the biggest of any private- sector UK company, is expected to pay out more than pounds 40 million in bonuses. The 106,000 staff included in the scheme will receive an extra four per cent on top of their pay. † (Shillingford 1999, p. 46). In order to attract more customers, managers of Tesco constantly consider the variety of products offered and new markets in which the company could start offering its products. They constantly check for new products which can be needed by customers. Tesco has got involved in the e-commerce business due to its increasing importance in the world. Overall, Tesco’s advantage in comparison with ASDA and Sainsbury can be summarized in the following way, according to Tesco’s deputy chairman: â€Å"If you wander around different stores, you might well be puzzled as to why one has higher revenues than another. The answer, I believe, depends to a large extent on how you deal with customers, which in turn depends on how you deal with your own staff. † (Child 2002: 137). Conclusion. Tesco currently occupies a highly competitive position in the world retailing market. Due to its well-balanced international strategy, the company has already expanded in many countries in Europe and Asia and increased the shareholders’ value as the result of these expansions. Tesco is growing faster than its competitors and thus needs to keep expand its activities internationally to obtain a larger share of the world market. Tesco has the highest growth potential in the industry of supermarket retailing, even in comparison with retailing giants which are much larger than Tesco by size. China gives Tesco a great opportunity for worldwide expansion because the number of consumers will be constantly growing in this country. Even though competition is currently large in Chinese market and represented by both local and international companies, Tesco is able to establish a firm position in this market by applying all of the tools which made it so successful in the domestic market and put at the top of the industry. Tesco has already expanded into many countries and it could search domination in such markets as, for example, Poland, Thailand, or South Korea. However, the growth potential of China is much larger than of the mentioned countries. By providing extensive investments into China and starting to conquer Chinese market, Tesco will be capable to ensure that its potential for growth in the following years will be fully realized. Bibliography. 1. Child Peter N. (2002), Taking Tesco Global: David Reid, Deputy Chairman of the United Kingdom’s Largest Grocer, Explains the Company’s International Strategy, The McKinsey Quarterly. Issue: 3. 2. Drucker, P. , (2001), Innovation and entrepreneurship, Oxford, Butterworth-Heinemann. 3. Fifield, P. , (1998), Marketing Strategy, Oxford, Butterworth Heinemann. 4. Kevan Reilly (1998), NO 1 TESCO PROVES SMALL IS BIGGEST; High Street Strategy Topples Arch Rival Sainsbury’s, The Mirror, May 5, 1998. 5. Senior, B., (1997). Organisational change, London, Pitman Publishing. 6. Shaw Stephen M. , Woetzel Jonathan R. (1992). A Fresh Look at China. The McKinsey Quarterly. Issue: 3. 7. Shillingford Joia (1999), TESCO STAFF CASH IN WITH Pounds 40m BONUSES, Sunday Mirror, April 11, 1999. 8. Britain’s biggest supermarket Tesco enters China’s mainland. Available at source: english. people. com. cn/200407/14/eng20040714_149590. html). 9. Tesco Ready to Wrestle in China. Available from source: http://www. english. people. com. cn/200403/16/eng20040316 ).